2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-107830R
    Methyl cholate (Standard)
    Methyl cholate (Standard) is the analytical standard of Methyl cholate. This product is intended for research and analytical applications. Methyl Cholate is methyl ester form of Cholic acid. Cholic acid is one of the major bile acids produced by the liver, where it is synthesized from cholesterol[1].
    Methyl cholate (Standard)
  • HY-B2121R
    6-Methoxy-2-naphthoic acid (Standard)
    6-Methoxy-2-naphthoic acid (Standard) (6-MNA (Standard)) is the analytical standard of 6-Methoxy-2-naphthoic acid (HY-B2121). This product is intended for research and analytical applications. 6-Methoxy-2-naphthoic acid (6-MNA) is the active metabolite of Nabumetone (HY-B0559). 6-Methoxy-2-naphthoic acid is also an inhibitor of COX-1 and COX-2. 6-Methoxy-2-naphthoic acid can inhibit the synthesis of gastric mucosal prostaglandin E2. 6-Methoxy-2-naphthoic acid can be used in the research of inflammation and pain-related diseases. In addition, 6-Methoxy-2-naphthoic acid is an impurity in Naproxen (HY-15030) and can also be used in the synthesis of other active compounds.
    6-Methoxy-2-naphthoic acid (Standard)
  • HY-W699907
    Pantoprazole sulfide-d8
    Pantoprazole sulfide-d8 is the deuterium labeled Pantoprazole sulfide (HY-W016033). Pantoprazole sulfide is a metabolite of Pantoprazole (HY-17507), which is a proton-pump inhibitor.
    Pantoprazole sulfide-d<sub>8</sub>
  • HY-135359R
    RP 48497 (Standard)
    Adenosine 5'-monophosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-monophosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes.
    RP 48497 (Standard)
  • HY-157690
    19(S),20(R)-EDP
    19(S),20(R)-EDP is an epoxidized metabolite of docosahexaenoic acid (HY-B2167).
    19(S),20(R)-EDP
  • HY-142122R
    Imipramine N-oxide (Standard)
    Imipramine N-oxide (Standard) is the analytical standard of Imipramine N-oxide. This product is intended for research and analytical applications. Imipramine N-oxide is the metabolite of Imipramine. Imipramine is a tertiary amine tricyclic antidepressant[1][2].
    Imipramine N-oxide (Standard)
  • HY-17528R
    Cyhalofop (Standard)
    Cyhalofop (Standard) is the analytical standard of Cyhalofop. This product is intended for research and analytical applications. Cyhalofop (Cyhalofop acid), the primary metabolite of Cyhalofop-butyl (HY-B0861) in susceptible grasses, is the herbicidally active metabolite. Cyhalofop-butyl is an aryloxyphenoxypropionate post-emergence herbicide widely used around the world in agriculture.
    Cyhalofop (Standard)
  • HY-W770677
    9-Carboxymethoxymethylguanine-13C2,15N
    9-Carboxymethoxymethylguanine-13C2,15N is the 13C- and 15N-labeled 9-Carboxymethoxymethylguanine (HY-137181). 9-Carboxymethoxymethylguanine is the main metabolite of Aciclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent.
    9-Carboxymethoxymethylguanine-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-W178868S
    Lodoxamide impurity 1-d5
    Lodoxamide impurity 1-d5 is deuterium labeled n-Ethyl-2-hydroxyacetamide.
    Lodoxamide impurity 1-d<sub>5</sub>
  • HY-13056R
    SMND-309 (Standard)
    Dimepiperate (Standard) is the analytical standard of Dimepiperate. This product is intended for research and analytical applications. Dimepiperate (MY 93) is a thiocarbamate (TC) pesticide. Dimepiperate has potential off-targets effect for the inhibition of ABHD6.
    SMND-309 (Standard)
  • HY-131270
    Febuxostat impurity 8
    Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM.
    Febuxostat impurity 8
  • HY-114656
    Dihydro-PGF1α
    Dihydro-PGF1α is a potential metabolite of PGF1α.
    Dihydro-PGF1α
  • HY-Z0081
    2S,4R-Sacubitril
    2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
    2S,4R-Sacubitril
  • HY-116787
    5-Hydroxythiabendazole
    5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure.
    5-Hydroxythiabendazole
  • HY-143992S
    Maytansinoid DM4 impurity 2-d6
    Maytansinoid DM4 impurity 2-d6 is the deuterium labeled Maytansinoid DM4 impurity 2.
    Maytansinoid DM4 impurity 2-d<sub>6</sub>
  • HY-148377
    Abiraterone sulfate N-oxide
    Abiraterone sulfate N-oxide is a carboxylic acid. Abiraterone sulfate N-oxide also is a major metabolite of Abiraterone (HY-70013). Abiraterone sulfate N-oxide can be used for the research of prostate cancer.
    Abiraterone sulfate N-oxide
  • HY-B0802AR
    Terbutaline (Standard)
    Benactyzine hydrochloride (Standard) is the analytical standard of Benactyzine hydrochloride. This product is intended for research and analytical applications. Benactyzine hydrochloride is a competitive BChE inhibitor with a Ki of 0.01 mM. Benactyzine hydrochloride is an anticholinergic drug. Benactyzine hydrochloride has the potential for organophosphate poisoning research.
    Terbutaline (Standard)
  • HY-W716321
    AN7602
    AN7602 is a metabolite of the anti-inflammatory agent/PDE4 inhibitor Crisaborole (HY-10978) and can be used for the study of mild to moderate atopic dermatitis (AD).
    AN7602
  • HY-W012481S
    Nirvanol-d5
    Nirvanol-d5 (Ethylphenylhydantoin-d5) is deuterium labeled Nirvanol (HY-W012481). Nirvanol (Ethylphenylhydantoin) is a metabolite of Mephenytoin (HY-B1184) that exerts anticonvulsant effects in the maximal electroshock (M.E.S.) seizure model in mice. Nirvanol shows potential for research in epilepsy-related neurological disorders.
    Nirvanol-d<sub>5</sub>
  • HY-131263
    Hydroxychloroquine Impurity F
    Hydroxychloroquine Impurity F is the impurity of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro.
    Hydroxychloroquine Impurity F
Cat. No. Product Name / Synonyms Application Reactivity